RHOB 抗体 (AA 104-137)
Our Local Distributor
北京 101111
Quick Overview for RHOB 抗体 (AA 104-137) (ABIN656198)
抗原
See all RHOB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 104-137
-
预测反应
- B, M, Rat
-
纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
-
免疫原
- This ARHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-137 amino acids from the Central region of human ARHB.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:4000. IHC-P: 1:10~50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- ARHB Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
-
有效期
- 6 months
-
-
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
-
别名
- ARHB
-
背景
- ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
-
分子量
- 22123
-
基因ID
- 388
-
NCBI登录号
- NP_004031
-
UniProt
- P62745
抗原
-