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PAK6 抗体 (AA 268-297)

This anti-PAK6 antibody is a 兔 多克隆 antibody detecting PAK6 in WB, IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN656098
发货至: 中国

Quick Overview for PAK6 抗体 (AA 268-297) (ABIN656098)

抗原

See all PAK6 抗体
PAK6 (P21-Activated Kinase 6 (PAK6))

适用

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宿主

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克隆类型

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多克隆

标记

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This PAK6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

克隆位点

RB31991
  • 抗原表位

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    AA 268-297

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PAK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the Central region of human PAK6.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PAK6 (P21-Activated Kinase 6 (PAK6))

    别名

    PAK6

    背景

    This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

    分子量

    74869

    基因ID

    56924

    NCBI登录号

    NP_001122100, NP_001122101, NP_001263646, NP_001263647, NP_064553

    UniProt

    Q9NQU5
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