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TGIF1 抗体 (AA 145-174)

This anti-TGIF1 antibody is a 兔 多克隆 antibody detecting TGIF1 in WB. Suitable for 人.
产品编号 ABIN656000
发货至: 中国

Quick Overview for TGIF1 抗体 (AA 145-174) (ABIN656000)

抗原

See all TGIF1 抗体
TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

适用

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宿主

  • 31
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克隆类型

  • 33
  • 5
多克隆

标记

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This TGIF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB14111
  • 抗原表位

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    AA 145-174

    预测反应

    C

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This TGIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human TGIF1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    别名

    TGIF1

    背景

    The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.

    分子量

    43013

    基因ID

    7050

    NCBI登录号

    NP_001265611, NP_001265613, NP_001265615, NP_003235, NP_733796, NP_775299, NP_775300, NP_775301, NP_775302, NP_775303, NP_777480

    UniProt

    Q15583

    途径

    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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