SIRPB1 抗体 (PE)
Quick Overview for SIRPB1 抗体 (PE) (ABIN6559830)
抗原
See all SIRPB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD172b PE
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特异性
- The mouse monoclonal antibody B4B6 recognizes an extracellular epitope of CD172b, an approximately 50 kDa transmembrane glycoprotein expressed on myeloid cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- NIH-3T3 cells transfected with human CD172b
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亚型
- IgG1
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anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-371) antibody
SIRPB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-206), (Isoform 3) antibodySIRPB1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) antibodySIRPB1 适用: 人, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 127-356) antibodySIRPB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 17-43), (N-Term) antibodySIRPB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB45115 unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) antibodySIRPB1 适用: 人 FACS 宿主: 小鼠 Monoclonal B4B6 unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 129-342) antibodySIRPB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
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别名
- CD172b
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背景
- Signal regulatory protein beta 1,CD172b, the signal-regulatory protein beta (SIRP beta) is a disulfide-linked homodimer expressed on myeloid cells including monocytes and dendritic cells. Similarly to CD172a, it serves as a negative regulator of tyrosine kinase-coupled signaling processes. Unlike CD172a, the CD172b protein does not possess the cytoplasmic domain, but instead its transmembrane domain can interact with another transmembrane protein DAP-12, which contains ITAM sequences in its intracellular domain and links CD172b to the downstream signaling molecules. The result is e.g. regulation of neutrophil transepithelial migration.,SIRPB1
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基因ID
- 10326
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UniProt
- O00241
抗原
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