电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PAX5 抗体 (AA 178-207)

This anti-PAX5 antibody is a Rabbit Polyclonal antibody detecting PAX5 in WB, FACS, IHC (p). Suitable for Human.
产品编号 ABIN655650
发货至: 中国

Quick Overview for PAX5 抗体 (AA 178-207) (ABIN655650)

抗原

See all PAX5 抗体
PAX5 (Paired Box 5 (PAX5))

适用

  • 107
  • 54
  • 10
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 85
  • 17
  • 5
  • 1

克隆类型

  • 74
  • 34
多克隆

标记

  • 64
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PAX5 antibody is un-conjugated

应用范围

  • 65
  • 46
  • 29
  • 15
  • 14
  • 14
  • 13
  • 10
  • 8
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB20217
  • 抗原表位

    • 15
    • 9
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 178-207

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PAX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the Central region of human PAX5.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PAX5 (Paired Box 5 (PAX5))

    别名

    PAX5

    背景

    This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.

    分子量

    42149

    基因ID

    5079

    NCBI登录号

    NP_001267476, NP_001267477, NP_001267478, NP_001267479, NP_001267481, NP_001267482, NP_001267483, NP_001267484, NP_001267485, NP_057953

    UniProt

    Q02548
You are here:
Chat with us!