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PCDHGA1 抗体 (AA 287-315)

This anti-PCDHGA1 antibody is a 兔 多克隆 antibody detecting PCDHGA1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN655609
发货至: 中国

Quick Overview for PCDHGA1 抗体 (AA 287-315) (ABIN655609)

抗原

See all PCDHGA1 抗体
PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))

适用

  • 10
  • 6

宿主

  • 8
  • 8

克隆类型

  • 8
  • 8
多克隆

标记

  • 7
  • 2
  • 2
  • 2
  • 2
  • 1
This PCDHGA1 antibody is un-conjugated

应用范围

  • 16
  • 14
  • 13
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB31763
  • 抗原表位

    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 287-315

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PCDHGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the Central region of human PCDHGA1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))

    别名

    PCDHGA1

    背景

    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

    分子量

    101226

    基因ID

    56114

    NCBI登录号

    NP_061735, NP_114382

    UniProt

    Q9Y5H4
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