Factor XI 抗体 (AA 281-307)
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Quick Overview for Factor XI 抗体 (AA 281-307) (ABIN655515)
抗原
See all Factor XI (F11) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 281-307
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This F11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-307 amino acids from the Central region of human F11.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Factor XI (F11) (Coagulation Factor XI (F11))
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别名
- F11
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背景
- This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].
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分子量
- 70109
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基因ID
- 2160
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NCBI登录号
- NP_000119
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UniProt
- P03951
抗原
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