OPN-A,b (AA 14-40), (N-Term) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in WB, IF 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 4+ publications.
(4 references)Quick Overview for OPN-A,b (AA 14-40), (N-Term) 抗体 (ABIN655514)
抗原
OPN-A,b
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
RB19160
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抗原表位
- AA 14-40, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This OPN-a/b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-40 amino acids from the N-terminal region of human OPN-a/b.
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亚型
- Ig Fraction
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应用备注
- IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes." in: Scientific reports, Vol. 6, pp. 25032, (2018) (PubMed).
: "NEAT1/miR-181c Regulates Osteopontin (OPN)-Mediated Synoviocyte Proliferation in Osteoarthritis." in: Journal of cellular biochemistry, Vol. 118, Issue 11, pp. 3775-3784, (2018) (PubMed).
: "MALAT1/miR-127-5p Regulates Osteopontin (OPN)-Mediated Proliferation of Human Chondrocytes Through PI3K/Akt Pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 431-439, (2018) (PubMed).
: "Osteopontin Promotes Expression of Matrix Metalloproteinase 13 through NF-κB Signaling in Osteoarthritis." in: BioMed research international, Vol. 2016, pp. 6345656, (2016) (PubMed).
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: "MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes." in: Scientific reports, Vol. 6, pp. 25032, (2018) (PubMed).
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- OPN-A,b
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背景
- Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).
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分子量
- 35423
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基因ID
- 6696
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NCBI登录号
- NP_000573, NP_001035147, NP_001035149, NP_001238758, NP_001238759
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UniProt
- P10451
抗原
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