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MITF 抗体 (N-Term)

Cited in 1 publication. This anti-MITF antibody is a 兔 多克隆 antibody detecting MITF in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN655506
发货至: 中国
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Quick Overview for MITF 抗体 (N-Term) (ABIN655506)

抗原

See all MITF 抗体
MITF (Microphthalmia-Associated Transcription Factor (MITF))

适用

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宿主

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克隆类型

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多克隆

标记

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This MITF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

RB18810
  • 抗原表位

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    AA 1-28, N-Term

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MITF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human MITF.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. WB: 1:2000. IHC: 1:800. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Ishii, Ryu, Suzuki: "Lactoferrin inhibits melanogenesis by down-regulating MITF in melanoma cells and normal melanocytes." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 95, Issue 1, pp. 119-125, (2017) (PubMed).

  • 抗原

    MITF (Microphthalmia-Associated Transcription Factor (MITF))

    别名

    MITF

    背景

    This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

    分子量

    58795

    基因ID

    4286

    NCBI登录号

    NP_000239, NP_001171896, NP_006713, NP_937801, NP_937802, NP_937820, NP_937821

    UniProt

    O75030

    途径

    Chromatin Binding
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