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GAD 抗体 (C-Term)

This anti-GAD antibody is a 兔 多克隆 antibody detecting GAD in WB. Suitable for 人.
产品编号 ABIN655175
发货至: 中国

Quick Overview for GAD 抗体 (C-Term) (ABIN655175)

抗原

See all GAD (GAD1) 抗体
GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

适用

  • 100
  • 66
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宿主

  • 93
  • 17
  • 3
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克隆类型

  • 90
  • 25
多克隆

标记

  • 62
  • 10
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  • 3
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  • 3
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  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This GAD antibody is un-conjugated

应用范围

  • 83
  • 40
  • 25
  • 18
  • 15
  • 13
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  • 7
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  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB19329
  • 抗原表位

    • 15
    • 11
    • 9
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
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    AA 514-543, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 514-543 amino acids from the C-terminal region of human GAD1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

    别名

    GAD1

    背景

    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

    分子量

    66897

    基因ID

    2571

    NCBI登录号

    NP_000808, NP_038473

    UniProt

    Q99259
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