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Endothelin 3 抗体 (C-Term)

This anti-Endothelin 3 antibody is a 兔 多克隆 antibody detecting Endothelin 3 in WB. Suitable for 人.
产品编号 ABIN655169
发货至: 中国

Quick Overview for Endothelin 3 抗体 (C-Term) (ABIN655169)

抗原

See all Endothelin 3 (EDN3) 抗体
Endothelin 3 (EDN3)

适用

  • 30
  • 4
  • 2
  • 2
  • 1
  • 1

宿主

  • 31
  • 3

克隆类型

  • 32
  • 2
多克隆

标记

  • 22
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Endothelin 3 antibody is un-conjugated

应用范围

  • 23
  • 13
  • 7
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)

克隆位点

RB18967
  • 抗原表位

    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 168-197, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This EDN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human EDN3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Endothelin 3 (EDN3)

    别名

    EDN3

    背景

    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

    分子量

    25454

    基因ID

    1908

    NCBI登录号

    NP_000105, NP_996915, NP_996916, NP_996917

    UniProt

    P14138

    途径

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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