TNFR-S274 (AA 252-281) 抗体
This 兔 多克隆 antibody specifically detects TNFR-S274 in FACS 和 WB. It exhibits reactivity toward 人.
产品编号 ABIN655093
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for TNFR-S274 (AA 252-281) 抗体 (ABIN655093)
抗原
TNFR-S274
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Flow Cytometry (FACS), Western Blotting (WB)
克隆位点
RB25825
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抗原表位
- AA 252-281
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TNFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from human TNFR.
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亚型
- Ig Fraction
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anti-TNFR-S274 antibody
适用: 人 FACS, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- TNFR-S274
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背景
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
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分子量
- 50495
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基因ID
- 7132
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NCBI登录号
- NP_001056
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UniProt
- P19438
抗原
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