ASXL1 抗体 (AA 521-549)
Quick Overview for ASXL1 抗体 (AA 521-549) (ABIN655084)
抗原
See all ASXL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 521-549
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ASXL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the Central region of human ASXL1.
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亚型
- Ig Fraction
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anti-Additional Sex Combs Like 1 (ASXL1) (AA 1-84) antibody
ASXL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E2 unconjugated
anti-Additional Sex Combs Like 1 (ASXL1) (AA 521-549) antibodyASXL1 适用: 人, 小鼠 WB, FACS, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Additional Sex Combs Like 1 (ASXL1) antibodyASXL1 适用: 人 DB 宿主: 小鼠 Monoclonal 2049C2a unconjugated
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应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- ASXL1 (Additional Sex Combs Like 1 (ASXL1))
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别名
- ASXL1
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背景
- This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.
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分子量
- 165432
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基因ID
- 171023
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NCBI登录号
- NP_056153
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UniProt
- Q8IXJ9
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途径
- Retinoic Acid Receptor Signaling Pathway
抗原
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