TNIP1 抗体 (C-Term)
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北京 101111
Quick Overview for TNIP1 抗体 (C-Term) (ABIN2844618)
抗原
See all TNIP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 454-482, C-Term
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TNIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human TNIP1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
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别名
- TNIP1
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背景
- Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal (By similarity). Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.
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分子量
- 71864
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基因ID
- 10318
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NCBI登录号
- NP_001239315, NP_001239319, NP_001239320, NP_001239321, NP_001239322, NP_001245383, NP_006049
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UniProt
- Q15025
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途径
- Activation of Innate immune Response
抗原
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