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Cyclin H 抗体 (C-Term)

This anti-Cyclin H antibody is a 兔 多克隆 antibody detecting Cyclin H in WB 和 FACS. Suitable for 人.
产品编号 ABIN654894
发货至: 中国

Quick Overview for Cyclin H 抗体 (C-Term) (ABIN654894)

抗原

See all Cyclin H (CCNH) 抗体
Cyclin H (CCNH)

适用

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宿主

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克隆类型

  • 64
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多克隆

标记

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This Cyclin H antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB14888
  • 抗原表位

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    AA 269-299, C-Term

    预测反应

    Pr

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CCNH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-299 amino acids from the C-terminal region of human CCNH.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Cyclin H (CCNH)

    别名

    CCNH

    背景

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.

    分子量

    37643

    基因ID

    902

    NCBI登录号

    NP_001230

    UniProt

    P51946

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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