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NSUN2 抗体 (AA 423-451)

This anti-NSUN2 antibody is a 兔 多克隆 antibody detecting NSUN2 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN654767
发货至: 中国

Quick Overview for NSUN2 抗体 (AA 423-451) (ABIN654767)

抗原

See all NSUN2 抗体
NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

适用

  • 26
  • 17
  • 9
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 26

克隆类型

  • 26
多克隆

标记

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
This NSUN2 antibody is un-conjugated

应用范围

  • 21
  • 17
  • 7
  • 7
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB28701
  • 抗原表位

    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 423-451

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This NSUN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 423-451 amino acids from the Central region of human NSUN2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

    别名

    NSUN2

    背景

    Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed 17071714]).

    分子量

    86471

    基因ID

    54888

    NCBI登录号

    NP_001180384, NP_060225

    UniProt

    Q08J23
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