CRYGS 抗体 (C-Term)
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Quick Overview for CRYGS 抗体 (C-Term) (ABIN654694)
抗原
See all CRYGS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 133-162, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CRYGS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the C-terminal region of human CRYGS.
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亚型
- Ig Fraction
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anti-Crystallin, gamma S (CRYGS) (AA 1-178) antibody
CRYGS 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, gamma S (CRYGS) (AA 2-178) antibodyCRYGS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, gamma S (CRYGS) antibodyCRYGS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, gamma S (CRYGS) (AA 1-178) antibodyCRYGS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- CRYGS (Crystallin, gamma S (CRYGS))
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别名
- CRYGS
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背景
- Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
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分子量
- 21007
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基因ID
- 1427
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NCBI登录号
- NP_060011
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UniProt
- P22914
抗原
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