GRIA4 抗体 (AA 259-287)
Our Local Distributor
北京 101111
Quick Overview for GRIA4 抗体 (AA 259-287) (ABIN654681)
抗原
See all GRIA4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 259-287
-
预测反应
- Pr, Rat
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This GRIA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human GRIA4.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:1000. IHC-P: 1:50~100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
-
别名
- GRIA4
-
背景
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq].
-
分子量
- 100871
-
基因ID
- 2893
-
NCBI登录号
- NP_000820, NP_001070711, NP_001070712, NP_001106283
-
UniProt
- P48058
-
途径
- PI3K-Akt Signaling
抗原
-