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IL12_2 (AA 756-783), (C-Term) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in FACS, WB 和 IHC (p). Suitable for 人.
产品编号 ABIN654644
发货至: 中国

Quick Overview for IL12_2 (AA 756-783), (C-Term) 抗体 (ABIN654644)

抗原

IL12_2

适用

宿主

克隆类型

多克隆

应用范围

Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB28530
  • 抗原表位

    AA 756-783, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This IL12_2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 756-783 amino acids from the C-terminal region of human IL12_2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    IL12_2

    背景

    The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.

    分子量

    97135

    基因ID

    3595

    NCBI登录号

    NP_001245143, NP_001245144, NP_001245145, NP_001550

    UniProt

    Q99665
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