IL12_2 (AA 756-783), (C-Term) 抗体
The 兔 多克隆 anti-IL12_2 antibody is suitable to detect IL12_2 in samples from 人. It has been validated for FACS, WB 和 IHC (p).
产品编号 ABIN654644
发货至:
中国
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Contact Info
Our Local Distributor
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北京 101111
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Quick Overview for IL12_2 (AA 756-783), (C-Term) 抗体 (ABIN654644)
抗原
IL12_2
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
RB28530
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抗原表位
- AA 756-783, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This IL12_2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 756-783 amino acids from the C-terminal region of human IL12_2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- IL12_2
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背景
- The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
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分子量
- 97135
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基因ID
- 3595
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NCBI登录号
- NP_001245143, NP_001245144, NP_001245145, NP_001550
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UniProt
- Q99665
抗原
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