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Cyclin T1 抗体 (AA 253-281)

This anti-Cyclin T1 antibody is a 兔 多克隆 antibody detecting Cyclin T1 in WB 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN654626
发货至: 中国

Quick Overview for Cyclin T1 抗体 (AA 253-281) (ABIN654626)

抗原

See all Cyclin T1 (CCNT1) 抗体
Cyclin T1 (CCNT1)

适用

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人, 小鼠

宿主

  • 36
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  • 1

克隆类型

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多克隆

标记

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This Cyclin T1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB19562
  • 抗原表位

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    AA 253-281

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids from the Central region of human CCNT1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Cyclin T1 (CCNT1)

    别名

    CCNT1

    背景

    CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.

    分子量

    80685

    基因ID

    904

    NCBI登录号

    NP_001231

    UniProt

    O60563
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