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CES2 抗体 (AA 340-369)

This anti-CES2 antibody is a 兔 多克隆 antibody detecting CES2 in WB, FACS 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN654618
发货至: 中国

Quick Overview for CES2 抗体 (AA 340-369) (ABIN654618)

抗原

See all CES2 抗体
CES2 (Carboxylesterase 2 (CES2))

适用

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宿主

  • 33
  • 7
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克隆类型

  • 40
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多克隆

标记

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This CES2 antibody is un-conjugated

应用范围

  • 37
  • 21
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  • 7
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  • 1
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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB18998
  • 抗原表位

    • 5
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    AA 340-369

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CES2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-369 amino acids from the Central region of human CES2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:25. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Shang, Liu, Chen, Ning, Xiong, Liu, Mao, Hu, Yang: "Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells." in: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-13, (2015) (PubMed).

    Chen, Wang, Ning, Hu, Liu, Xiong, Wu, Liu, Hu, Yang: "Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1?/Stra13 pathway." in: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-12, (2015) (PubMed).

  • 抗原

    CES2 (Carboxylesterase 2 (CES2))

    别名

    CES2

    背景

    CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.

    分子量

    61807

    基因ID

    8824

    NCBI登录号

    NP_003860, NP_932327

    UniProt

    O00748
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