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E2F2 抗体 (AA 258-286)

This anti-E2F2 antibody is a 兔 多克隆 antibody detecting E2F2 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN654438
发货至: 中国
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Quick Overview for E2F2 抗体 (AA 258-286) (ABIN654438)

抗原

See all E2F2 抗体
E2F2 (E2F Transcription Factor 2 (E2F2))

适用

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人, 小鼠

宿主

  • 61
  • 7

克隆类型

  • 45
  • 23
多克隆

标记

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This E2F2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB27633
  • 抗原表位

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    AA 258-286

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This E2F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-286 amino acids from the Central region of human E2F2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    E2F2 (E2F Transcription Factor 2 (E2F2))

    别名

    E2F2

    背景

    E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq].

    分子量

    47506

    基因ID

    1870

    NCBI登录号

    NP_004082

    UniProt

    Q14209

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
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