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DENND1B 抗体 (N-Term)

This anti-DENND1B antibody is a 兔 多克隆 antibody detecting DENND1B in WB, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN654339
发货至: 中国

Quick Overview for DENND1B 抗体 (N-Term) (ABIN654339)

抗原

See all DENND1B 抗体
DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

适用

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宿主

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克隆类型

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多克隆

标记

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This DENND1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB28056
  • 抗原表位

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    AA 39-68, N-Term

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DENND1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))

    别名

    DENND1B

    背景

    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).

    分子量

    86552

    基因ID

    163486

    NCBI登录号

    NP_001182144, NP_001182145, NP_659414

    UniProt

    Q6P3S1
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