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AMH 抗体 (AA 424-451)

Cited in 2+ publications. This anti-AMH antibody is a 兔 多克隆 antibody detecting AMH in WB, FACS 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN653897
发货至: 中国
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Quick Overview for AMH 抗体 (AA 424-451) (ABIN653897)

抗原

See all AMH 抗体
AMH (Anti-Mullerian Hormone (AMH))

适用

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人, 小鼠

宿主

  • 84
  • 51
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克隆类型

  • 81
  • 57
多克隆

标记

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This AMH antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 12
    • 8
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    AA 424-451

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This AMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-451 amino acids of human AMH.

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:2000. IHC-P: 1:25. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Jin, Won, Park, Lee, Park, Bae: "FOXL2 Is an Essential Activator of SF-1-Induced Transcriptional Regulation of Anti-Müllerian Hormone in Human Granulosa Cells." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159112, (2017) (PubMed).

    Park, Suh, Lee, Bae: "Positive cross talk between FOXL2 and antimüllerian hormone regulates ovarian reserve." in: Fertility and sterility, (2014) (PubMed).

  • 抗原

    AMH (Anti-Mullerian Hormone (AMH))

    别名

    AMH

    背景

    Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.

    分子量

    59195

    基因ID

    268

    NCBI登录号

    NP_000470

    UniProt

    P03971

    途径

    Negative Regulation of Hormone Secretion
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