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MARCO 抗体 (AA 13-40)

Cited in 2+ publications. The 兔 多克隆 anti-MARCO antibody (Clone RB24662) (ABIN653847) specifically detects MARCO in WB, FACS 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN653847
发货至: 中国
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Quick Overview for MARCO 抗体 (AA 13-40) (ABIN653847)

抗原

See all MARCO 抗体
MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

适用

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宿主

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克隆类型

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多克隆

标记

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This MARCO antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB24662
  • 抗原表位

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    AA 13-40

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MARCO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids of human MARCO.

    亚型

    IgG
  • 应用备注

    WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Ohta, Moriyama, Maehara, Gion, Furukawa, Tanaka, Hayashida, Yamauchi, Ishiguro, Mikami, Tsuboi, Iizuka-Koga, Kawano, Sato, Kiyoshima, Sumida, Nakamura: "DNA Microarray Analysis of Submandibular Glands in IgG4-Related Disease Indicates a Role for MARCO and Other Innate Immune-Related Proteins." in: Medicine, Vol. 95, Issue 7, pp. e2853, (2016) (PubMed).

    Chao, Makale, Karmali, Sharikov, Tsigelny, Merkulov, Kesari, Wrasidlo, Ruoslahti, Simberg: "Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains." in: Bioconjugate chemistry, Vol. 23, Issue 5, pp. 1003-9, (2014) (PubMed).

  • 抗原

    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

    别名

    MARCO

    背景

    MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

    分子量

    52658

    基因ID

    8685

    NCBI登录号

    NP_006761

    UniProt

    Q9UEW3

    途径

    Activation of Innate immune Response
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