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GRPR 抗体 (AA 123-152)

This anti-GRPR antibody is a 兔 多克隆 antibody detecting GRPR in IHC (p). Suitable for 人.
产品编号 ABIN2843048
发货至: 中国

Quick Overview for GRPR 抗体 (AA 123-152) (ABIN2843048)

抗原

See all GRPR 抗体
GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

适用

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宿主

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克隆类型

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多克隆

标记

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This GRPR antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB24634
  • 抗原表位

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    AA 123-152

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GRPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-152 amino acids from the Central region of human GRPR.

    亚型

    IgG
  • 应用备注

    IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

    别名

    GRPR

    背景

    Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

    分子量

    43199

    基因ID

    2925

    NCBI登录号

    NP_005305

    UniProt

    P30550
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