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PDHA1 抗体 (AA 226-255)

This anti-PDHA1 antibody is a 兔 多克隆 antibody detecting PDHA1 in WB. Suitable for 人.
产品编号 ABIN653604
发货至: 中国

Quick Overview for PDHA1 抗体 (AA 226-255) (ABIN653604)

抗原

See all PDHA1 抗体
PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

适用

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宿主

  • 95
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克隆类型

  • 86
  • 22
多克隆

标记

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This PDHA1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB24303
  • 抗原表位

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    AA 226-255

    预测反应

    Zf, B, Pr, M, Pig, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PDHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-255 amino acids from the Central region of human PDHA1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

    别名

    PDHA1

    背景

    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome.

    分子量

    43296

    基因ID

    5160

    NCBI登录号

    NP_000275, NP_001166925, NP_001166926, NP_001166927

    UniProt

    P08559

    途径

    Warburg Effect
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