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ADRA1B 抗体 (AA 270-297)

This 兔 多克隆 anti-ADRA1B antibody (Clone RB25170) specifically detects ADRA1B in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN653353
发货至: 中国
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Quick Overview for ADRA1B 抗体 (AA 270-297) (ABIN653353)

抗原

See all ADRA1B 抗体
ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

适用

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宿主

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克隆类型

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多克隆

标记

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This ADRA1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB25170
  • 抗原表位

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    AA 270-297

    预测反应

    B, M, Rb, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human ADRA1B.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

    别名

    ADRA1B

    背景

    Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

    分子量

    56836

    基因ID

    147

    NCBI登录号

    NP_000670

    UniProt

    P35368

    途径

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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