T-Box 1 抗体 (C-Term)
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Quick Overview for T-Box 1 抗体 (C-Term) (ABIN653331)
抗原
See all T-Box 1 (TBX1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 327-356, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 327-356 amino acids from the C-terminal region of human TBX1.
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亚型
- Ig Fraction
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应用备注
- IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- T-Box 1 (TBX1)
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别名
- TBX1
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背景
- TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 43133
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基因ID
- 6899
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NCBI登录号
- NP_005983, NP_542377, NP_542378
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UniProt
- O43435
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途径
- Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
抗原
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