SRC8 抗体 (N-Term)
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北京 101111
Quick Overview for SRC8 抗体 (N-Term) (ABIN653194)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 9-38, N-Term
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预测反应
- C, M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SRC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human SRC8.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- SRC8 (SRC8 Protein (SRC8))
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别名
- SRC8
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背景
- SRC8 is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This protein has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this protein contributes to tumor cell invasion and metastasis.
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分子量
- 61586
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基因ID
- 2017
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NCBI登录号
- NP_001171669, NP_005222, NP_612632
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UniProt
- Q14247
抗原
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