CIRBP 抗体 (C-Term)
Quick Overview for CIRBP 抗体 (C-Term) (ABIN653083)
抗原
See all CIRBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 145-172, C-Term
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预测反应
- Ha, M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CIRBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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Cold-inducible RNA-binding protein mediates cold air inducible airway mucin production through TLR4/NF-κB signaling pathway." in: International immunopharmacology, Vol. 39, pp. 48-56, (2017) (PubMed).
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Cold-inducible RNA-binding protein mediates cold air inducible airway mucin production through TLR4/NF-κB signaling pathway." in: International immunopharmacology, Vol. 39, pp. 48-56, (2017) (PubMed).
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- CIRBP (Cold Inducible RNA Binding Protein (CIRBP))
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别名
- CIRBP
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背景
- CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor (By similarity) and promotes assembly of stress granules (SGs), when overexpressed.
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分子量
- 18648
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基因ID
- 1153
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NCBI登录号
- NP_001271
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UniProt
- Q14011
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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