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CIRBP 抗体 (C-Term)

This anti-CIRBP antibody is a 兔 多克隆 antibody detecting CIRBP in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN653083
发货至: 中国

Quick Overview for CIRBP 抗体 (C-Term) (ABIN653083)

抗原

See all CIRBP 抗体
CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

适用

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宿主

  • 47
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克隆类型

  • 45
  • 9
多克隆

标记

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This CIRBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB23135
  • 抗原表位

    • 15
    • 7
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    • 1
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    AA 145-172, C-Term

    预测反应

    Ha, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CIRBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Chen, Ran, Xie, Xu, Zhou: "Cold-inducible RNA-binding protein mediates cold air inducible airway mucin production through TLR4/NF-κB signaling pathway." in: International immunopharmacology, Vol. 39, pp. 48-56, (2017) (PubMed).

  • 抗原

    CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

    别名

    CIRBP

    背景

    CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor (By similarity) and promotes assembly of stress granules (SGs), when overexpressed.

    分子量

    18648

    基因ID

    1153

    NCBI登录号

    NP_001271

    UniProt

    Q14011

    途径

    Ribonucleoprotein Complex Subunit Organization
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