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GCLM 抗体 (C-Term)

This anti-GCLM antibody is a 兔 多克隆 antibody detecting GCLM in WB, IF, FACS 和 IHC (p). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN653046
发货至: 中国

Quick Overview for GCLM 抗体 (C-Term) (ABIN653046)

抗原

See all GCLM 抗体
GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

适用

  • 63
  • 36
  • 30
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 61
  • 8

克隆类型

  • 50
  • 19
多克隆

标记

  • 40
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
This GCLM antibody is un-conjugated

应用范围

  • 45
  • 33
  • 25
  • 17
  • 15
  • 14
  • 12
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB22980
  • 抗原表位

    • 12
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 246-274, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GCLM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the C-terminal region of human GCLM.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. WB: 1:1000. WB: 1:8000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Chen, Jiang, Hu, Zhang: "The protective role of resveratrol in the sodium arsenite-induced oxidative damage via modulation of intracellular GSH homeostasis." in: Biological trace element research, Vol. 155, Issue 1, pp. 119-31, (2014) (PubMed).

  • 抗原

    GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

    别名

    GCLM

    背景

    GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

    分子量

    30727

    基因ID

    2730

    NCBI登录号

    NP_002052

    UniProt

    P48507
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