FBLN3 抗体 (N-Term)
Quick Overview for FBLN3 抗体 (N-Term) (ABIN653039)
抗原
See all FBLN3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 119-148, N-Term
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预测反应
- Pr, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This EFEMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the N-terminal region of human EFEMP1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway." in: Oncotarget, Vol. 6, Issue 16, pp. 14191-208, (2016) (PubMed).
: "Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats." in: International journal of clinical and experimental medicine, Vol. 8, Issue 2, pp. 2118-27, (2015) (PubMed).
: "Anti-EGFR function of EFEMP1 in glioma cells and patient prognosis." in: Oncoscience, Vol. 1, Issue 3, pp. 205-15, (2015) (PubMed).
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: "EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway." in: Oncotarget, Vol. 6, Issue 16, pp. 14191-208, (2016) (PubMed).
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- FBLN3 (Fibulin 3 (FBLN3))
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别名
- EFEMP1
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背景
- EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors.
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分子量
- 54641
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基因ID
- 2202
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NCBI登录号
- NP_001034437, NP_001034438
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UniProt
- Q12805
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途径
- EGFR Signaling Pathway
抗原
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