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FBLN3 抗体 (N-Term)

Cited in 3+ publications. This anti-FBLN3 antibody is a 兔 多克隆 antibody detecting FBLN3 in WB, IHC (p) 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN653039
发货至: 中国
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Quick Overview for FBLN3 抗体 (N-Term) (ABIN653039)

抗原

See all FBLN3 抗体
FBLN3 (Fibulin 3 (FBLN3))

适用

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人, 小鼠

宿主

  • 54
  • 10

克隆类型

  • 45
  • 19
多克隆

标记

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This FBLN3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB22140
  • 抗原表位

    • 8
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    AA 119-148, N-Term

    预测反应

    Pr, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This EFEMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the N-terminal region of human EFEMP1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Wang, Cao, Huang, Ke, Luo, Lin, Wang, Zhang, Wang: "EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway." in: Oncotarget, Vol. 6, Issue 16, pp. 14191-208, (2016) (PubMed).

    Lin, Wang, Zhu, Li, Xie, Xiang: "Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats." in: International journal of clinical and experimental medicine, Vol. 8, Issue 2, pp. 2118-27, (2015) (PubMed).

    Hu, Gao, Vo, Ke, Pan, Yu, Siegel, Hess, Linskey, Zhou: "Anti-EGFR function of EFEMP1 in glioma cells and patient prognosis." in: Oncoscience, Vol. 1, Issue 3, pp. 205-15, (2015) (PubMed).

  • 抗原

    FBLN3 (Fibulin 3 (FBLN3))

    别名

    EFEMP1

    背景

    EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors.

    分子量

    54641

    基因ID

    2202

    NCBI登录号

    NP_001034437, NP_001034438

    UniProt

    Q12805

    途径

    EGFR Signaling Pathway
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