LDLR 抗体 (AA 391-419)
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北京 101111
Quick Overview for LDLR 抗体 (AA 391-419) (ABIN652907)
抗原
See all LDLR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 391-419
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预测反应
- X, B, Ha, Pig, Rb, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids of human LDLR.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- LDLR (Low Density Lipoprotein Receptor (LDLR))
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别名
- LDLR
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背景
- The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
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分子量
- 95376
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基因ID
- 3949
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NCBI登录号
- NP_000518, NP_001182727, NP_001182728, NP_001182729, NP_001182732
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UniProt
- P01130
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途径
- Hepatitis C, Lipid Metabolism
抗原
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