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UNC13B 抗体 (AA 1062-1091)

Cited in 1 publication. This 兔 多克隆 anti-UNC13B antibody (Clone RB22476) specifically detects UNC13B in WB 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN652852
发货至: 中国
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Quick Overview for UNC13B 抗体 (AA 1062-1091) (ABIN652852)

抗原

See all UNC13B 抗体
UNC13B (Unc-13 Homolog B (UNC13B))

适用

  • 31
  • 14
  • 3
  • 1

宿主

  • 36
  • 2
  • 1
  • 1

克隆类型

  • 39
  • 1
多克隆

标记

  • 21
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UNC13B antibody is un-conjugated

应用范围

  • 27
  • 21
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

RB22476
  • 抗原表位

    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1062-1091

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Kasmapour, Gronow, Bleck, Hong, Gutierrez: "Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 50, pp. 20485-90, (2012) (PubMed).

  • 抗原

    UNC13B (Unc-13 Homolog B (UNC13B))

    别名

    UNC13B

    背景

    UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).

    分子量

    180679

    基因ID

    10497

    NCBI登录号

    NP_006368

    UniProt

    O14795

    途径

    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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