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MFN2 抗体 (AA 447-476)

This anti-MFN2 antibody is a 兔 多克隆 antibody detecting MFN2 in WB, IHC (p) 和 FACS. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN652786
发货至: 中国

Quick Overview for MFN2 抗体 (AA 447-476) (ABIN652786)

抗原

See all MFN2 抗体
MFN2 (Mitofusin 2 (MFN2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This MFN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB21136
  • 抗原表位

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    AA 447-476

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 447-476 amino acids from the Central region of human MFN2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:25. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Zhou, Zhang, He, Zhuang, Han, Jiang, Yao, Huang, Ling, Lin, Lin: "Downregulation of mitochondrial cyclooxygenase-2 inhibits the stemness of nasopharyngeal carcinoma by decreasing the activity of dynamin-related protein 1." in: Theranostics, Vol. 7, Issue 5, pp. 1389-1406, (2018) (PubMed).

    Yamauchi, Yamamura, Katase, Itadani, Okada, Kobiki, Nakamura, Yamaguchi, Kuribayashi: "Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device." in: BMC cancer, Vol. 17, Issue 1, pp. 234, (2017) (PubMed).

  • 抗原

    MFN2 (Mitofusin 2 (MFN2))

    别名

    MFN2

    背景

    MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system.

    分子量

    86402

    基因ID

    9927

    NCBI登录号

    NP_001121132, NP_055689

    UniProt

    O95140

    途径

    Skeletal Muscle Fiber Development
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