Importin 11 抗体 (N-Term)
Quick Overview for Importin 11 抗体 (N-Term) (ABIN652718)
抗原
See all Importin 11 (IPO11) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 56-85, N-Term
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This IPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human IPO11.
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亚型
- Ig Fraction
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anti-Importin 11 (IPO11) antibody
IPO11 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Importin 11 (IPO11) antibodyIPO11 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 1-50) antibodyIPO11 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 328-377) antibodyIPO11 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Importin 11 (IPO11) (AA 776-975) antibodyIPO11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Importin 11 (IPO11)
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别名
- IPO11
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背景
- IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).
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分子量
- 112535
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基因ID
- 51194
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NCBI登录号
- NP_001128251, NP_057422
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UniProt
- Q9UI26
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途径
- Protein targeting to Nucleus
抗原
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