Quick Overview for BDK_1 (AA 213-239) 抗体 (ABIN652683)
抗原
BDK_1
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Flow Cytometry (FACS), Western Blotting (WB)
克隆位点
RB21729
抗原表位
AA 213-239
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This BDK_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the Central region of human BDK_1.
亚型
Ig Fraction
应用备注
WB: 1:1000. FC: 1:10~50
限制
仅限研究用
状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
抗原
BDK_1
背景
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.