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Protein Tob1 (TOB1) (AA 54-83), (N-Term) 抗体

This anti-Protein Tob1 antibody is a 兔 多克隆 antibody detecting Protein Tob1 in WB, IHC (p) 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN652511
发货至: 中国
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Quick Overview for Protein Tob1 (TOB1) (AA 54-83), (N-Term) 抗体 (ABIN652511)

抗原

See all Protein Tob1 (TOB1) 抗体
Protein Tob1 (TOB1)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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非结合性

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB19906
  • 抗原表位

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    AA 54-83, N-Term

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TOB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human TOB1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Protein Tob1 (TOB1)

    别名

    TOB1

    背景

    TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.

    分子量

    38155

    基因ID

    10140

    NCBI登录号

    NP_001230806, NP_001230814, NP_005740

    UniProt

    P50616
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