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SREBF chaperone 抗体 (AA 604-632)

This anti-SREBF chaperone antibody is a 兔 多克隆 antibody detecting SREBF chaperone in WB, IF, IHC (p) 和 FACS. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN652508
发货至: 中国

Quick Overview for SREBF chaperone 抗体 (AA 604-632) (ABIN652508)

抗原

See all SREBF chaperone (SCAP) 抗体
SREBF chaperone (SCAP)

适用

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  • 1
人, 小鼠, 大鼠

宿主

  • 39
  • 2

克隆类型

  • 39
  • 2
多克隆

标记

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  • 1
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  • 1
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  • 1
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This SREBF chaperone antibody is un-conjugated

应用范围

  • 32
  • 13
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  • 12
  • 5
  • 3
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  • 3
  • 2
  • 2
  • 1
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  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB22508
  • 抗原表位

    • 15
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 604-632

    预测反应

    B, Pig

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This SCAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-632 amino acids from the Central region of human SCAP.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:100. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:25. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Takashima, Saitoh, Funabashi, Hirose, Yagi, Nozaki, Sato, Shin, Nakayama: "COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions." in: Journal of cell science, Vol. 128, Issue 15, pp. 2805-15, (2015) (PubMed).

  • 抗原

    SREBF chaperone (SCAP)

    别名

    SCAP

    背景

    SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

    分子量

    139729

    基因ID

    22937

    NCBI登录号

    NP_036367

    UniProt

    Q12770

    途径

    SARS-CoV-2 Protein Interactome
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