SREBF chaperone 抗体 (AA 604-632)
Our Local Distributor
北京 101111
Quick Overview for SREBF chaperone 抗体 (AA 604-632) (ABIN652508)
抗原
See all SREBF chaperone (SCAP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 604-632
-
预测反应
- B, Pig
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This SCAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-632 amino acids from the Central region of human SCAP.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- IF: 1:100. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:25. FC: 1:25
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
-
: "COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions." in: Journal of cell science, Vol. 128, Issue 15, pp. 2805-15, (2015) (PubMed).
-
: "COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions." in: Journal of cell science, Vol. 128, Issue 15, pp. 2805-15, (2015) (PubMed).
-
- SREBF chaperone (SCAP)
-
别名
- SCAP
-
背景
- SCAP is a protein with a sterol sensing domain(SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
-
分子量
- 139729
-
基因ID
- 22937
-
NCBI登录号
- NP_036367
-
UniProt
- Q12770
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-