This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ACTR3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-352 amino acids from the C-terminal region of human ACTR3B.
ACTR3B plays a role in the organization of the actin cytoskeleton. It may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks and may decrease the metastatic potential of tumors.