PLA2G4A 抗体 (AA 513-541)
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北京 101111
Quick Overview for PLA2G4A 抗体 (AA 513-541) (ABIN652449)
抗原
See all PLA2G4A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 513-541
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预测反应
- C, Zf, Hs, M, Rb, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PLA2G4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-541 amino acids from the Central region of human PLA2G4A.
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亚型
- Ig Fraction
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应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
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别名
- PLA2G4A
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背景
- PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
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分子量
- 85239
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基因ID
- 5321
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NCBI登录号
- NP_077734
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UniProt
- P47712
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途径
- Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
抗原
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