MUC20 抗体 (N-Term)
Quick Overview for MUC20 抗体 (N-Term) (ABIN652399)
抗原
See all MUC20 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 61-90, N-Term
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This MUC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human MUC20.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- IF: 1:10~50. WB: 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 6 months
-
-
-
: "Comprehensive assessment of genetic variants within TCF4 in Fuchs' endothelial corneal dystrophy." in: Investigative ophthalmology & visual science, Vol. 55, Issue 9, pp. 6101-7, (2014) (PubMed).
: "Expression analysis of the transmembrane mucin MUC20 in human corneal and conjunctival epithelia." in: Investigative ophthalmology & visual science, Vol. 55, Issue 10, pp. 6132-8, (2014) (PubMed).
-
: "Comprehensive assessment of genetic variants within TCF4 in Fuchs' endothelial corneal dystrophy." in: Investigative ophthalmology & visual science, Vol. 55, Issue 9, pp. 6101-7, (2014) (PubMed).
-
- MUC20 (Mucin 20, Cell Surface Associated (MUC20))
-
别名
- MUC20
-
背景
- This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.
-
分子量
- 71982
-
基因ID
- 200958
-
UniProt
- Q8N307
抗原
-