TrkA-pY791 (AA 769-796) 抗体
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北京 101111
Quick Overview for TrkA-pY791 (AA 769-796) 抗体 (ABIN652381)
抗原
适用
宿主
克隆类型
应用范围
克隆位点
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抗原表位
- AA 769-796
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TrkA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 769-796 amino acids from human TrkA.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:10~50. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- TrkA-pY791
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背景
- TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
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分子量
- 87497
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基因ID
- 4914
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NCBI登录号
- NP_001007793, NP_001012331, NP_002520
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UniProt
- P04629
抗原
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