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SPHK1 抗体 (C-Term)

This anti-SPHK1 antibody is a 兔 多克隆 antibody detecting SPHK1 in WB, FACS 和 IHC (p). Suitable for 人.
产品编号 ABIN652302
发货至: 中国

Quick Overview for SPHK1 抗体 (C-Term) (ABIN652302)

抗原

See all SPHK1 抗体
SPHK1 (Sphingosine Kinase 1 (SPHK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SPHK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB15395
  • 抗原表位

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    AA 313-343, C-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This SPHK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-343 amino acids from the C-terminal region of human SPHK1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    SPHK1 (Sphingosine Kinase 1 (SPHK1))

    别名

    SPHK1

    背景

    SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.

    基因ID

    8877

    NCBI登录号

    NP_001136073, NP_001136074, NP_068807, NP_892010

    UniProt

    Q9NYA1

    途径

    VEGF Signaling
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