Metabotropic Glutamate Receptor 1 抗体 (C-Term)
Quick Overview for Metabotropic Glutamate Receptor 1 抗体 (C-Term) (ABIN652203)
抗原
See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1096-1126, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Metabotropic Glutamate Receptor 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1096-1126 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 1.
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亚型
- Ig Fraction
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anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 165-592) antibody
GRM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 501-516), (Extracellular) antibodyGRM1 适用: 大鼠 WB, IP, IF, IC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) antibodyGRM1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5E12D8 unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 880-1017) antibodyGRM1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (C-Term) antibodyGRM1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (N-Term) antibodyGRM1 适用: 人, Cow, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (Internal Region) antibodyGRM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca
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有效期
- 6 months
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- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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别名
- Metabotropic Glutamate Receptor 1 (GPRC1A)
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背景
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 (also known as GPRC1A) and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The activity of GRM1 is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. This protein may participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum
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分子量
- 132357
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基因ID
- 2911
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NCBI登录号
- NP_001264993, NP_001264994, NP_001264995, NP_001264996
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UniProt
- Q13255
抗原
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