SIRT3 抗体 (C-Term)
Quick Overview for SIRT3 抗体 (C-Term) (ABIN652184)
抗原
See all SIRT3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 304-334, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Sirt3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-334 amino acids from the C-terminal region of Mouse Sirt3.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. WB: 1:64000. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
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有效期
- 6 months
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: "Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD." in: PLoS ONE, Vol. 10, Issue 3, pp. e0118909, (2015) (PubMed).
: "Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest." in: The Journal of clinical investigation, Vol. 120, Issue 8, pp. 2817-28, (2010) (PubMed).
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: "Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD." in: PLoS ONE, Vol. 10, Issue 3, pp. e0118909, (2015) (PubMed).
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- SIRT3 (Sirtuin 3 (SIRT3))
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别名
- Sirt3
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背景
- SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.
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分子量
- 36615
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基因ID
- 64384
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NCBI登录号
- NP_001120823, NP_001171275, NP_071878
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UniProt
- Q8R104
抗原
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