ARHGEF3 抗体 (AA 211-240)
(1 reference)Quick Overview for ARHGEF3 抗体 (AA 211-240) (ABIN652003)
抗原
See all ARHGEF3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 211-240
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ARHGEF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human ARHGEF3.
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亚型
- Ig Fraction
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 287-526) antibody
ARHGEF3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 33-142) antibodyARHGEF3 适用: 人 ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) antibodyARHGEF3 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 287-526) antibodyARHGEF3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (AA 1-324) antibodyARHGEF3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) (C-Term) antibodyARHGEF3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." in: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).
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: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." in: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).
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- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
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别名
- ARHGEF3
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背景
- Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 59783
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基因ID
- 50650
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NCBI登录号
- NP_001122087, NP_001122088, NP_062455
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UniProt
- Q9NR81
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途径
- Neurotrophin Signaling Pathway
抗原
-
