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FOXP2 抗体 (AA 657-684)

This anti-FOXP2 antibody is a 兔 多克隆 antibody detecting FOXP2 in WB 和 IF. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN651939
发货至: 中国

Quick Overview for FOXP2 抗体 (AA 657-684) (ABIN651939)

抗原

See all FOXP2 抗体
FOXP2 (Forkhead Box P2 (FOXP2))

适用

  • 45
  • 23
  • 14
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 33
  • 7
  • 3
  • 2
  • 1

克隆类型

  • 35
  • 10
  • 1
多克隆

标记

  • 32
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FOXP2 antibody is un-conjugated

应用范围

  • 31
  • 25
  • 12
  • 8
  • 7
  • 6
  • 5
  • 2
Western Blotting (WB), Immunofluorescence (IF)

克隆位点

RB21207
  • 抗原表位

    • 10
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 657-684

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This FOXP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-684 amino acids of human FOXP2.

    亚型

    IgG
  • 应用备注

    IF: 1:10~50. WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Vibulyaseck, Fujita, Luo, Tran, Oh-Nishi, Ono, Hirano, Sugihara: "Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum." in: The Journal of comparative neurology, Vol. 525, Issue 14, pp. 2971-2990, (2018) (PubMed).

    Fujita, Morita, Furuichi, Sugihara: "Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 45, pp. 15688-703, (2012) (PubMed).

  • 抗原

    FOXP2 (Forkhead Box P2 (FOXP2))

    别名

    FOXP2

    背景

    FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

    分子量

    79919

    基因ID

    93986

    NCBI登录号

    NP_001166237, NP_001166238, NP_055306, NP_683696, NP_683697, NP_683698

    UniProt

    O15409
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