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IPO7 抗体 (N-Term)

This anti-IPO7 antibody is a 兔 多克隆 antibody detecting IPO7 in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN2840333
发货至: 中国

Quick Overview for IPO7 抗体 (N-Term) (ABIN2840333)

抗原

See all IPO7 抗体
IPO7 (Importin 7 (IPO7))

适用

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  • 21
  • 4
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  • 3
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  • 2
  • 2
  • 1
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  • 1
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  • 1
人, 小鼠

宿主

  • 43
  • 1

克隆类型

  • 43
  • 1
多克隆

标记

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  • 3
  • 2
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  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
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This IPO7 antibody is un-conjugated

应用范围

  • 37
  • 14
  • 13
  • 13
  • 13
  • 9
  • 4
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB26876
  • 抗原表位

    • 15
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 142-169, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This IPO7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the N-terminal region of human IPO7.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    IPO7 (Importin 7 (IPO7))

    别名

    IPO7

    背景

    The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

    分子量

    119517

    基因ID

    10527

    NCBI登录号

    NP_006382

    UniProt

    O95373

    途径

    Protein targeting to Nucleus
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